biodistribution study japanbiodistribution study japan
Recently, there has been speculation regarding potential safety signals associated with COVID-19 mRNA vaccines. I am giving you the technical version so you can see for yourself the actual data reviewed by EMA. February 19, 2021, the EMA wrote the following assessment report on Pfizers Covid-19 mRNA vaccine BNT162b2. -. SARS-CoV-2 mRNA Vaccine (BNT162, PF-07302048) 2.6.4 PFIZERCONFIDENTIAL Page 3 1. BNT162b2BioNTechBNT162PfizerPF-07302048 To conduct BD studies, it is necessary to understand regulatory requirements, implementation status, and analytical methods. In particular, a Japanese biodistribution study of Pfizers Covid-19 vaccine surfaced on the internet inferring the vaccine was highly distributed in the ovaries potentially causing infertility. 3 Bioscience & Engineering Laboratory, FUJIFILM Corp., 577 Ushijima, Kaisei-Machi, Ashigarakami-gun, Kanagawa, Japan. We do not have all the animal or clinical data needed to completely evaluate long term safety of the mRNA vaccines. Vaccine Researcher Admits Big Mistake, Says Spike Protein Is Dangerous Toxin.. All of these risk factors have something in common: Theyre all associated with mitochondrial dysfunction. Other research suggests the SARS-CoV-2 spike protein can have a serious impact on your mitochondrial function, which is imperative for good health, innate immunity and disease prevention of all kinds. This is about as diabolical as it gets. Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Consensus treatment plans for induction therapy of newly diagnosed proliferative lupus nephritis in juvenile systemic lupus erythematosus. DNA Extraction Method Affects the Detection of a Fungal Pathogen in Formalin-Fixed Specimens Using qPCR. What is the real truth? Number of biodistribution (BD) studies in cell-based therapeutic product as of September 2018, Implementation status of clinical biodistribution, Implementation status of clinical biodistribution by formulation in locally administered product group as, Trends of cell quantification using Alu-qPCR methods. I thought this would be an easy blog to write, cut and dry. Hello do you have an updated link to the old Japanese Pfizer study? When blood clots completely block a blood vessel, you end up with a stroke or a heart attack. 2009 Aug;(144):3-79. So, by vaccinating people we are inadvertently inoculating them with a toxin.. https://t.co/bvncGZWV4v pic.twitter.com/aNxH6bkAS5. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. When an immune response is launched against the spike protein, the virus stops infecting the body. It is a toxin that can cause damage in our body if it gets into circulation. Why the confusion? Elaborating on the implications of these findings, he remarked: We have known for a long time that the spike protein is a pathogenic protein. To do that, you need to become metabolically flexible and optimize your diet. Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizer's biodistribution study from the Japanese regulatory agency. Future Perspectives for Factor V Deficiency Using Recombinant and Advanced Therapies. Please read and agree to the disclaimer before watching this video.. SARS-COV-2 Spikes in Ovaries from Pfizer-BioNTech Vaccine?There has been some uncertaint. Read our disclaimer for details. There are many different types of vasculitis, including Kawasakis disease, antiphospholipid syndrome, rheumatoid arthritis, scleroderma and Sjogrens disease. It is true that some of experiments looked at the distribution of lipid nanoparticles containing an mRNA coding for Luciferase, a protein that exhibits bioluminescence allowing for visualization where the mRNA ended up. Adams AJ, LaBonte JP, Ball ML, Richards-Hrdlicka KL, Toothman MH, Briggs CJ. The biodistribution was also studied in rats, using radiolabeled LNP and luciferase modRNA (study 185350. Biomarkers Biomarkers are not evaluated in this study.***, Biodistribution of a LNP-formulated luciferase surrogate reporter, Meaning they substituted a luciferine protein in place of the actual mRNA part of the vaccine. In the case of covid-19 vaccines, regulators accepted biodistribution data from past studies performed with related, mostly unapproved compounds that use the same platform technology. 2012 Mar;64(3):375-83. doi: 10.1002/acr.21558. What is the clinical outcome? He explained that, through cutting edge, peer-reviewed science, weve learned more about the many problems associated with spike proteins and COVID-19 vaccines: The SARS-CoV-2 has aspike protein on its surface. Breastfeeding women also need to know that both the vaccine and the spike protein are being expelled in breast milk, and this could be lethal for their babies. sharing sensitive information, make sure youre on a federal Because the synthetic mRNA in the vaccine has been programmed to instruct your cells to produce an unnatural, genetically engineered spike protein. Support responsible news and fact-based information today! Biodistribution (BD) analysis is performed to determine the distribution and the persistence of the vector/virus to target and nontarget tissues following direct in vivo administration in animals. Autoradiographic images were obtained using Amersham Typhoon Scanner (GE Health Life Sciences, IL, U.S.A.). Why are these questions surfacing now? It is false to claim that Pfizer's biodistribution study showed lipid nanoparticles accumulating in the highest concentration in the ovaries. The European Medicine Agency (EMA) is an agency of the European Union (EU) in charge of the Evaluation and Supervison of Medicinal Products. New Peer Reviewed Study on COVID-19 Vaccines Suggests Why Heart Inflammation, Blood Clots and Other Dangerous Side Effects Occur. PMC I live in Japan. Brief Summary: The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants. Using Luciferine to follow biodistribution of a product is common practice. HHS Vulnerability Disclosure, Help As part of that research, he and a team of international scientists requested a Freedom of Information Act (FOIA) access to Pfizer's biodistribution study from the Japanese regulatory agency. The objective of this guideline is to provide harmonised recommendations for the conduct of nonclinical biodistribution (BD) studies in the development of gene therapy (GT) products. Yet he was 100% correct. When administered, COVID-19 vaccines are injected into the shoulder musclenot into the blood. All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. Low levels of radioactivity were detected in most tissues, with the greatest levels in plasma observed 1-4 hours post-dose. Theres also evidence suggesting the SARS-CoV-2 spike protein may be a prion, which is yet another piece of really bad news, particularly as it pertains to vaccine-induced spike protein. You are transferring the vaccine itself, as well as the spike protein, which could result in bleeding and/or blood clots in your child. The biodistribution study of [89 Zr]Zr-DFO-TST001 demonstrated favorable pharmacokinetics with a relatively long half-life in vivo (Fig. Princess Bajrakitiyabha of Thailand collapses, Vaxxed and unvaxxed coming down with same ailments, Sasha Latypova reveals COVID law and contracts, Todd Callender explains the legal framework for pandemics, Sasha Latypova gives a speech in Stockholm, Centers for Disease Control and Prevention, Fact Sheet for Healthcare Providers Administering Vaccine, https://www.fda.gov/media/144413/download, https://uncoverdc.com/wp-content/uploads/2021/05/Bridle.pdf.pagespeed.ce.aKOeaMY9Wh.pdf, https://omny.fm/shows/on-point-with-alex-pierson/new-peer-reviewed-study-on-covid-19-vaccines-sugge, https://www.lifesitenews.com/news/vaccine-researcher-admits-big-mistake-says-spike-protein-is-dangerous-toxin/, https://trialsitenews.com/did-pfizer-fail-to-perform-industry-standard-animal-testing-prior-to-initiation-of-mrna-clinical-trials/, https://www.youtube.com/watch?v=Du2wm5nhTXY, https://www.bitchute.com/video/UfFOTCxRORsp/, https://www.bitchute.com/video/T71ZVNAXi0jW/, https://rumble.com/v15oqc7-dr.-richard-urso-the-explosion-of-cancer-and-latent-disease-from-the-vaccin.html, First case of autopsy in a patient vaccinated against COVID-19, Report: mRNA vaccines is converted to DNA in the liver, Vaccine-Induced Covid-19 Mimicry Syndrome, Brian Gerrish explains the psychological manipulation of the public . People will continue to gather evidence supporting the vaccine, and people will continue to gather evidence against the vaccine. Fill in your details below or click an icon to log in: You are commenting using your WordPress.com account. Japanese government and Pfizer biodistribution study shows 75% of mRNA travels from injection site into blood and distributed into organs and across brain-blood barrier Trying to post again as original post was removed by automod for unknown reasons. After the protein piece is made, the cell breaks down the instructions and gets rid of them. (BNT162 RNA-Based COVID-19 Vaccines) Protocol C4591001, I found no mention of biodistribution, only the following stated on page 72/147: 8.5. I want to pass it on to some doctors in Japan who have no idea about its existence. It can cause damage in our body if it gets into circulation The spike protein on its own is almost entirely responsible for the damage to the cardiovascular system, if it gets into circulation.. All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. The petition and its supporting documents can be downloaded from the FDA website here: https://www.regulations.gov/docket/FDA-2021-P-0521/document, However, information regarding biodistribution of the Pfizer vaccine in animal studies was referenced by the European Medicine Agencys (EMA) review of Pfizers mRNA vaccine data sent to them by Pfizer. Using Luciferine to follow biodistribution of a product is common practice. However, a Japanese document of the Pfizer vaccine data showed biodistribution beyond the local injection site, with distribution highest in the ovaries at 48 hours. Data were . The signal decreased slowly during the first 72 hours and after 6 and 9 days the signals were further weakened to approximately levels of 18 and 7 times the signals obtained from animals injected with buffer control. Characteristics of Extracellular Vesicles and Preclinical Testing Considerations Prior to Clinical Applications. The https:// ensures that you are connecting to the Information about the cons of the vaccines is very difficult to find. Remember to check the date when the fact-check you are reading was published before sharing it. Change). It is important that your sauna is hot enough (around 170 degrees Fahrenheit) and does not have high magnetic or electric fields. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. You can view The Poynter Institutes most-recent public financial disclosure form 990, Poynter ACES Introductory Certificate in Editing. The study is titled, "Placebo-controlled randomized double-blind (evaluators, patients) multi-facility joint parallel-group comparison . Federal government websites often end in .gov or .mil. In biodistribution study, two groups of SD rats (15 rats/sex/group) were injected intramuscularly with AdC68-19S 2 10 11 vp (twofold the proposed clinical dose of 1 10 11 vp/dose) or vehicle, respectively, on day 1. The greatest mean concentration was found remaining in the injection site at each time point in both sexes. When the spike protein interacts with the ACE2 receptor, it can disrupt mitochondrial signaling, thereby inducing the production of reactive oxygen species and oxidative stress. Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF; Health Review Committee. Pingback: Lying to children - Change is Always Possible. According to this study, there was no difference in ovarian function between those who were infected with the Covid-19 and those who were not. -, Gu E., Chen W.Y., Gu J., Burridge P., Wu J.C. Molecular imaging of stem cells: tracking survival, biodistribution, tumorigenicity, and immunogenicity. SARS-CoV-2which has been shown to cross the blood-brain barrier in mice and cause many kinds of heart, blood vessel, and brain damagehas a spike protein on its surface, allowing the virus to infect our bodies. government site. Pfizer's biodistribution study for Japanese . After spending 20 hours of research, I found there are no animal biodistribution studies of mRNA vaccines done by Pfizer, Moderna, or J and J published on an internet search. 2018;7(1):7886. Content Deleted, Powerful Billionaires Threaten Mercola, The Strange, New Pattern Showing Up After COVID Vaccine, New World Order Yields to the Great Reset, Worse Than The Disease: Reviewing Some Possible Unintended Consequences of mRNA Vaccines Against COVID-19, Princess of Thailand Potential Heiress to the Throne, Grassley: How My Investigation Into Biden Family Financial Dealings Was Sabo taged, Train Derailment Ground Zero Eye Report, New Palestine Train Derailment and Hazardous Materials, Mike Adams Editorial on Destruction of the Nordstream Pipeline, How America Took Out the Nordstream Pipeline, Reporter Seymour Hersh on How America Took Out the Nord Stream Pipeline: Exclusive TV Interview. which is it, did they or did they now know that the spike protein was a toxin/pathogenic for a long time? After spending 20 hours of research, I found there are. . As of August 23, 2021, the Pfizer-BioNTech inoculation is now approved under the brand name Comirnaty. Parkinsons disease is a prion disease that has been traced back to prions originating in the spleen, that then travel up to the brain via the vagus nerve. No safety pharmacology studies were conducted with BNT162b2. Next, LPP formulated with mRNA encoding luciferase as a model. When a substance is injected into the body, tracking where it goes- its biodistribution is important to know. No traditional pharmacokinetic or biodistribution studies have been performed with the vaccine candidate BNT162b2. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. Okay I just noticed the link please ignore. 8600 Rockville Pike When that happens, it can do one of two things: it can either cause platelets to clump, and that can lead to clottingthats exactly why weve been seeing clotting disorders associated with these vaccines. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Japanese Regulatory Agency study VAX SPIKE PROTEIN concentrates in spleen, liver, adrenals, and ovaries in high concentrations 2nd Study shows breast milk contamination, infants encountering bleeding disorders in the gastrointestinal tract, reveals various cardiovascular and heart problems, Lying to children - Change is Always Possible, 13th June MUST SEE VIDEOS & DOCUMENTS: Based Amy, Vaccine Shedding: The Harm for Those Who Choose NOT to be Vaccinated - The Hollywood Conservative, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated - TruthMatters.biz, Breaking News Round Up Continues As The Old Traditional Rite Mass & Sacraments Become Restricted By Pope Francis | Traditional Catholics Emerge, A Secular Perspective on Gods Judgment Anonymous, 7/30/21 | pomegranatesandchains, LA School District Mandates COVID Jabs for All Students 12 and Older - Vaccine Effects, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated The Courtenay Turner Podcast, Kanye Wests love of Hitler allegedly goes back decades a well-known but well-keptsecret, 5 G Towers Spark Outrage Across New York City Harm shown in studies including cancer, infertility, and injury to fetuses andnewborns, A sneering Candace Owens thanks the Jewish men who promoted her career, by aligning herself with billionaire Anti-Semite Kanye West Rabbi Boteach denounces Prager and Shapiro for continuing to defend the scamartist, Jeffrey Epstein, Bill Clinton, Ghislane Maxwell, George Bush, Eugenics, the WEF, Transhumanism, China and the creation of a new class of slaves | Interview with Whitney WebbVIDEO, How Hitchcocks Documentary Masterpiece on the Holocaust was Censored as a political inconvenience inBritain, Britain Tried to Send Jewish Holocaust Survivors Back to Germany for Internment, Released DocumentsShow, 'Grand Mufti of Jerusalem' Haj Amin Al-Husseini, Organization of Islamic Cooperation (OIC). PLoS One. As part of that research, he and a team of international scientists requested a Freedom of Information Act (FOIA) access to Pfizers biodistribution study from the Japanese regulatory agency. Spike protein does not attack anything, it only aims to activate the immune response, it is not the same as coronavirus spike protein and after vaccination, it is created in a dose 100 thousand times lower than in viral infection. Shockingly, according to Bridle, the COVID-19 vaccine is different from traditional vaccines. SARS coronavirus 2 (SARS-CoV-2) enters cell by attaching to angiotensin converting enzyme 2 (ACE2) receptors on cell surface Following infection, there is internalization and downregulation of ACE2 receptors. You can also boost your sulfate by taking Epsom salt baths. You are not transferring antibodies. Remember to check the date when the fact-check you are reading was published before sharing it. Please send me all info on any new updates. . 2015;43(1):115125. Vitamin D Part I: Is Vitamin D really a vitamin? A biodistribution study was conducted using ddY mice (male, 5 weeks old). The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines, The assumption that vaccine developers have been working with is that the mRNA in the vaccines would primarily remain in and around the vaccination site. They confirmed what I had found. But, as you can see below, unlike Bridle, Politifact neglected to go beyond interviewing someone with such a huge stake in the vaccines success. Thus, a low ACE2 activity subsequent to SARS-CoV-2 infection leads to imbalance in renin-angiotensin system with relative excess of angiotensin II. 8.6. Study Design Go to Resource links provided by the National Library of Medicine MedlinePlus Genetics related topics: Alzheimer disease Trends of cell quantification using Alu-qPCR methods. No evidence of vaccine-related macroscopic or microscopic findings were found in the ovaries in the repeat-dose toxicity studies (Study 38166 and Study 20GR142), were identified in the DART, Developmental and Reproductive Toxicology, study.*, The bottom line is mRNA Covid vaccines are still considered experimental by the FDA as. Dr. Bridle, Associate Professor of Viral Immunology at the University of Guelph,received funding to develop a novel vaccine platform and is very much pro-vaccine.
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