Earlier this year, Hormones Matter published two posts suggesting that thiamine could be helpful in treating COVID-19, one by Dr. Lonsdale focused on the role of thiamine in facilitating the energy metabolism needed to fight disease and one by me focused on thiamines potential to increase oxygen levels through the inhibition of carbonic anhydrase isoenzymes. Cell Immunol. Cognizant of the prevailing view that RCTs are the best way to build evidence about the effects of medical treatment, the authors of the scientific review of the MATH+ protocol specifically discuss their decision to forgo an RCT. This post reviews the new evidence and argues for the accelerated execution of a randomized controlled trial to evaluate the potential of thiamine to slow the progression of COVID-19 in newly diagnosed outpatients. Malone discovered famotidines efficacy during his first run-in with covid in February 2020. This is a very intriguing post. Some say another mutation could occur; others that it would only make the virus less pathogenic. CO2 might also preserve cardiac function during systemic hypoxia. So, for those readers who may be physicians with Longhauler patients, Dr. Syed uses prednisolone, as . Testament to what Syed sees as medicines and governments utter failure to treat, he said the doctor told him approval would be needed from an infectious disease physician. Summary: the FLCCC Alliance in collaboration with Dr Bruce Patterson/Dr Yo and Dr Tina Peers (Mast Cell Activation Syndrome) and Dr Mobeen Syed (YouTube educator) have been working for some time on organizing a protocol for long haulers. I took the drug under the direction of Dr. Boros, whotreated his first patientby cellphone in July of 2020 in a hospital that refused to give the prescription Boros had delivered. The Malones, who are both in their sixties, were better within about a week. Learn how your comment data is processed. You must be logged in to give a plus1 award. By all indications, the U.S. and Europewhere a west-to-east tidal wave is unfoldingwill follow the South Africa-United Kingdom model. 3. Been), a prolific medical educator and Youtube personalitywho primarily reported using it as a preventive in the second week of acute infection, but found it can also resolve long haul COVID symptoms. Monoclonal Antibodies:I was nearly better when, on day five of symptoms, I got the infusion. I am optimistic for this, said Dr. Harvey Risch, a Yale epidemiologist and treatment advocate. How embarrassing and shameful, he said, that even approved covid drugs are not available. Given the price, side effect profile and various contraindications, it is lower down on the list of options and is unlikely to be necessary for most patients. If no IVM, he wrote in an email, then use famotidine80 milligrams a day. McCullough himself took ivermectin and hydroxychloroquine among other drugs for his covid infection, which I documented in anOctober 2020article. (His updated Omicron protocol is shown below. Testament to what Syed sees as medicines and governments utter failure to treat, he said the doctor told him approval would be needed from an infectious disease physician. They had seen specialists ranging from cardiologists to neurologists, pulmonologists to rheumatologists, endocrinologists to gastroenterologists and all had come up empty, in many cases finally telling them that it was just all in their heads the usual fall back when every test comes back negative and the syndrome hasnt been seen before. Three U.S. customers told me the company delivered without a problem. In a large new. The MATH+ protocol has not been evaluated through a randomized controlled trial, but the authors have published a detailed scientific review of the protocol as well as data on the mortality of patients treated with the protocol. Famotidine:This was recommended to me by Dr. Malone and is the only drug I took outside the FLCCC protocol; Dr. Kory told me he doesnt see enough data yet to support it. The promise of diagnostic tests is that not only will we have verifiable evidence confirming the diagnosis, but we can track changes during treatment and in cases where symptoms disappear and the testing still shows abnormalities, with a trend towards improvement, we might choose to continue therapy until the underlying abnormalities completely resolve in the hopes of curing the illness and thereby preventing recurrences. Many have been desperately seeking answers for months. So what should patients take if they cannot get ivermectin, I asked Dr. Peter McCullough, a crusader for early, sequential, multi-drug covid treatment? Two days ago, I received this text from the New York State Health Department: Anyone 12+ who received their Pfizer second dose at least five months ago is now eligible for a COVID booster. While not specifically addressed in the paper, this raises the question of whether the use of high doses of thiamine in individuals without a deficiency could have a similar effect in interrupting the disease cycle of a virus that depends on the thiamine transporter. Symptoms are frequently severe, debilitating, life changing. Thank you, especially for listing Dr. McCullough's treatment plan -- this makes it so easy for people to assemble their kit or 'toolbox. quadrupling and quintupling in thirty-fivestates from last winters peak. But even without such access, I would have known what to do. Dr. Mobeen Syed has repeatedly said in his videos and on Twitter here that he treats his LongCovid patients with a steroid pulse: Deltacortril (i.e. The protocol, I-RECOVER, is based on the group's . Trouble sleeping is nearly universal. Dr. Richard Fleming is the original proponent of the now mainstream inflammatory model of cardiovascular disease pathogenesis. Many patients report cleaning up their diet and lifestyle can partially or completely resolve long haul symptoms. In my experience combining too many treatments together is not as effective as choosing the most likely to work and be tolerable and using that on its own. Th17 Response and Inflammatory Autoimmune Diseases, International Journal of Inflammation, vol. 1. Carbonic anhydrase inhibitors produce carbon dioxide, which can help to reduce the hypoxic conditions that produce inflammation. And overall there are many bright rays of hope on the horizon for the long suffering long haulers out there. Omicron is undoubtedly different from the Delta variant that had sorely tested the early treatment portfolio. How many other doctors, who mostly follow the mainstream dogma against such treatments, would have accomplished that, let alone tried? For months, I had been taking vitamins C and, , and quercetin, along with glutathione and n-acetylcycstine in Horowitz protocol, with benefits I, When I took sick, I continued these supplements and added a few more from the FLCCC list, including. Many vaccine injured have found it impossible to get any help from experts at the NIH or from their local clinicians or university researchers. Dr. Syed shares. C. When T Cells Run Out of Breath: The HIF-1a Story. The vagus nerve is part of the parasympathetic system and its neurotransmitter is acetylcholine. I did contemplate the effects of my dying. Starting with last summers myth about poison-control centers overwhelmed with ivermectin calls, the struggle to obtain ivermectin has intensified. As a journalist who has covered the pandemic since March, 2020, I am fortunate to know doctors who reject the sicken-in-place, see-you-at-the-ER mentality. The beauty of this: All of these are readily available online or in specialty stores. The therapeutic effect here is likely based on its powerful anti-inflammatory action. More likely to cause side effects than the first two options. The outstanding reporting by Mary Beth Pfeiffer will be simultaneously published in both outlets. As a nurse I particularly love your drawings. Cavaleri even said, quite astonishingly, that too many boosters could impair the immune system. NAC N-Acetylcysteine. The list goes on and unlike the mortality numbers it is not so much the very elderly who are suffering, it is preteens up through the middle aged that are hit the hardest at least in terms of who is showing up. Dr. Mobeen Syed. IncellDx used machine learning to find a specific long COVID diagnostic signature based on characteristic changes in various inflammatory markers and in numbers of various immune system cells in patients with long COVID. Neither the Th17 study nor the scientific review of the MATH+ protocol mention thiamines role as a carbonic anhydrase inhibitor, but it is noted in two of the other articles referenced above as potentially contributing to reduced hypoxia. Could High-Dose Thiamine Reduce Mortality from COVID-19? We need to think about how we can transition from the current pandemic setting to a more endemic setting, Marco Cavaleri, chief of the European Unions vaccines committee saidin a press briefingJanuary 13, pointing squarely at Omicron. Already there are some indications that severe long term damage has occurred in many who have supposedly recovered. I am optimistic for this, said Dr. Harvey Risch, a Yale epidemiologist and treatment advocate. 4. The panel will be moderated by Dr. Mobeen Syed, CEO and Founder of DrBeen.com and DrBeen Online Medical Education. Marbles eight months of anosmia had resolved with the supplement. Al Sulaiman, K et. al. In experimental rheumatoid arthritis, thiamine increased the ability of corticosteroids to suppress production of TNF- and IL-6.. ), Patients in the UK and Canada report similar problems, while Australia has, ivermectin for covid. The beauty of this: All of these are readily available online or in specialty stores. In my experience the partial responders and non-responders at 2 days reach complete resolution within a month. Very methodical and straightforward. Experts are anxiously waiting for that to happen in exploding Omicron hot spots like the United States. I feel like I would not be here if it wasnt for her, Nick James said. Nevertheless, the comparatively low mortality rates of the hospitals using the MATH+ protocols represent very promising results. M.S. A thiamine deficiency syndrome, beriberi, bears a number of similarities to sepsis, including peripheral vasodilation, cardiac dysfunction, and elevated lactate levels. I feel like I would not be here if it wasnt for her, Nick James said. Your videos make everything so understandable and you explain the how and the why so clearly. The lesson: Do not trust the pharmacy system to work. Because ivermectin is so difficult [to get], using the protocols without ivermectin does become a rational thing to do, said Dr. Paul Marik, a founder of FLCCC, in an interview. Both diseases have been denied and mismanaged in a corrupt health care system. In other words, it would take nearly three-quarter million Omicron patients to equal the number who died in that sample of roughly Delta 17,000 patients. The most important new data are: (1) a study which found that high-dose thiamine lowers the Th17 cell proinflammatory response believed to be associated with the COVID-19 cytokine storm and (2) data on mortality rates from two medical centers using the MATH+ protocol to treat COVID-19 hospitalized patients. These include an advanced blood panel and whole body nuclear imaging. I was nearly better when, on day five of symptoms, I got the infusion. No hospitalizations, deaths, or vents!. ARWY For example: the current top-voted topic is "Safe and effective". Fluvoxamine 50mg once or twice a day for 14 days especially useful for brain fog and other neurological symptoms as it crosses the blood brain barrier and has a therapeutic effect in the brain. The withholding of known remedies is a crime of magnitude by government Intro by Kieron McFadden SOURCE: Liberty Rising The problem with Ivermectin used in conjunction with Vitamin D, C and Zinc is that had . The median dose of thiamine was 100 mg daily and the median duration of thiamine administration was 7 days. As a journalist who has covered the pandemic since March, 2020, I am fortunate to know doctors who reject the sicken-in-place, see-you-at-the-ER mentality. The U.S. and first-world governments still do not want doctors to treat covid early and are doing all it can to stop them. A reduction of acetylcholine would therefore affect this neurological control of inflammation, thus explaining the therapeutic potential of thiamine. promises a likely unnecessary Omicron vaccine by March. Dr. Mobeen Syed, at home January 14, 2022, recovering from a likely Omicron infection. COVID Reinfection Outcomes Are Not Good (Preprint Study) youtube.com. But it also can defy the fabled just-a-cold description that, in some cases, may not call for treatment. 5. Dr. Boros said he is making no predictions for the future, while Dr. McCullough said he simply did not know if Omicron will end the pandemic. In a recent interview with Dr. Mobeen Syed, Prevention101 discussed preventive measures against contracting Covid-19 infections as well as Long Haul disorders from home. Since the brain to some extent affects the functioning of every organ, inflammation and dysfunction within the brain could be the root cause of many widespread symptoms. Relatively recent research has shown that inflammation is controlled by the vagus nerve in its contact with the spleen. Many had been to multiple specialists and had million dollar workups, including Chest CT scans, Brain MRIs, exercise stress tests, pulmonary function tests, echocardiograms, doppler ultrasounds, scores of blood tests, allergy testing, and on and on. Cheap and safe if there is no history of bleeding, stomach ulcers, varices (enlarged blood vessels in the stomach or esophagus that are prone to bleeding) or liver failure. He returned to work as an insurance agent in Iowa the next week; she went back to her clinic. https://elemental.medium.com/covid-19-is-looking-more-and-more-like-an-autoimmune-disease-b6c563f8da24, (a) An updated version of the Clinical and Scientific Rationale for the MATH+ Hospital Treatment Protocol for COVID-19 has been published in the Journal of Intensive Care Medicine, at this link: https://journals.sagepub.com/doi/abs/10.1177/0885066620973585, (b) The first (to my knowledge) randomized trial of high-dose thiamine for fatigue has been published. They are easy to follow and help me make sense of complicated processes. And oftentimes the symptoms disappear with treatment only to resurface weeks later. Eventually these patients had come to the suspicion that their symptoms might in some way be related to an earlier COVID-19 infection. Dr Mobeen Syed of DrBeen.com reports that after treating 400 patients with ivermectin and a short course of low dose steroids during their acute illness, none but one progressed to long COVID, and that patient started treatment relatively late in his disease course. The drawings made it make sense. So, when he who tested positive for covid last week, he asked his personal physician about government-approved early treatments such as monoclonal antibodies,paxlovid, andmolnupiravir. Mobeen Syed is the CEO of Drbeen Corp, a modern online medical education marketplace. Many people my agenorth of sixtyhave suffered greatly, and some have died because they were not treated at first symptoms. Brain fog is a common complaint. Marbles eight months of anosmia had resolved with the supplement. Patients in the UK and Canada report similar problems, while Australia has prohibited ivermectin for covid. We have a very limited supply, the doctor told him. GOVERNMENT The withholding of known remedies is a crime of magnitude by government March 30, 2021 1. The data reviewed in this post add to the evidence base supporting a randomized controlled trial (RCT) to test whether thiamine alone or in combination with other agents could help to slow the progression of COVID-19 and/or mitigate the cytokine storm associated with some of its worst effects. 2023's exciting new method! There, Omicron rose and fell fast, obliterating the more fearsome Delta, and leading to far lower rates of hospitalization and death. 2016;303:715. But even without such access, I would have known what to do. the selective serotonin reuptake inhibitors (SSRIs), due to the increased possibility of adverse effects. Every intervention sends the body a message and it is possible to send mixed signals and not get anywhere despite choosing therapeutics that work like a charm when used separately. Thats the bad news, but only sort of.Subscribe to the Trialsitenews COVID-19 ChannelNo spam we promise. But its not just generic drugs that are hard to get. It was available back then to people my age. You are helping to change that, Dr. MoBeen. Thank you !!!! Chronic fatigue is frequent. The FLCCC and American Association of Physicians and Surgeons also post lists of doctors. (The company did not respond to three requests for an explanation.). Jan 11. It works as an anti-inflammatory and balances the immune system. So, when he tested positive for covid last week, he asked his personal physician about government-approved early treatments such as monoclonal antibodies, paxlovid, and molnupiravir. For the long suffering long haulers out there complicated processes Omicron is undoubtedly different from the Delta variant that sorely... Health care system for his covid infection, which I documented in anOctober 2020article me make sense complicated... 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